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Farnesoid X receptor activation by bile acids suppresses lipid peroxidation and ferroptosis

Ferroptosis is a regulated cell death modality that occurs upon iron-dependent lipid peroxidation. Recent research has identified many regulators that induce or inhibit ferroptosis; yet, many regulatory processes and networks remain to be elucidated. In this study, we performed a chemical genetics s...

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Detalles Bibliográficos
Autores principales: Tschuck, Juliane, Theilacker, Lea, Rothenaigner, Ina, Weiß, Stefanie A. I., Akdogan, Banu, Lam, Van Thanh, Müller, Constanze, Graf, Roman, Brandner, Stefanie, Pütz, Christian, Rieder, Tamara, Schmitt-Kopplin, Philippe, Vincendeau, Michelle, Zischka, Hans, Schorpp, Kenji, Hadian, Kamyar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10616197/
https://www.ncbi.nlm.nih.gov/pubmed/37903763
http://dx.doi.org/10.1038/s41467-023-42702-8