Loss of Histone Methyltransferase KMT2D Attenuates Angiogenesis in the Ischemic Heart by Inhibiting the Transcriptional Activation of VEGF-A

Angiogenesis occurred after myocardial infarction (MI) protects heart failure (HF). The aim of our study was to explore function of histone methyltransferase KMT2D (MLL4, mixed-lineage leukemia 4) in angiogenesis post-MI. Western blotting showed that KMT2D protein expression was elevated in MI mouse...

Descripción completa

Detalles Bibliográficos
Autores principales: Meng, Xiang-Min, Liu, Shu-Bao, Deng, Tian, Li, De-Yong, You, Lu, Hong, Hao, Feng, Qi-Pu, Zhu, Bing-Mei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10616223/
https://www.ncbi.nlm.nih.gov/pubmed/36947365
http://dx.doi.org/10.1007/s12265-023-10373-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10616223/
https://www.ncbi.nlm.nih.gov/pubmed/36947365
http://dx.doi.org/10.1007/s12265-023-10373-x

Ejemplares similares