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Loss of Histone Methyltransferase KMT2D Attenuates Angiogenesis in the Ischemic Heart by Inhibiting the Transcriptional Activation of VEGF-A

Angiogenesis occurred after myocardial infarction (MI) protects heart failure (HF). The aim of our study was to explore function of histone methyltransferase KMT2D (MLL4, mixed-lineage leukemia 4) in angiogenesis post-MI. Western blotting showed that KMT2D protein expression was elevated in MI mouse...

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Detalles Bibliográficos
Autores principales:	Meng, Xiang-Min, Liu, Shu-Bao, Deng, Tian, Li, De-Yong, You, Lu, Hong, Hao, Feng, Qi-Pu, Zhu, Bing-Mei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer US 2023
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10616223/ https://www.ncbi.nlm.nih.gov/pubmed/36947365 http://dx.doi.org/10.1007/s12265-023-10373-x

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