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Correlative CD4 and CD8 T-cell immunodominance in humans and mice: Implications for preclinical testing
Antigen-specific T-cell recognition is restricted by Major Histocompatibility Complex (MHC) molecules, and differences between CD4 and CD8 immunogenicity in humans and animal species used in preclinical vaccine testing are yet to be fully understood. In this study, we addressed this matter by analyz...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10616275/ https://www.ncbi.nlm.nih.gov/pubmed/37726420 http://dx.doi.org/10.1038/s41423-023-01083-0 |