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Correlative CD4 and CD8 T-cell immunodominance in humans and mice: Implications for preclinical testing

Antigen-specific T-cell recognition is restricted by Major Histocompatibility Complex (MHC) molecules, and differences between CD4 and CD8 immunogenicity in humans and animal species used in preclinical vaccine testing are yet to be fully understood. In this study, we addressed this matter by analyz...

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Detalles Bibliográficos
Autores principales: Neto, Tertuliano Alves Pereira, Sidney, John, Grifoni, Alba, Sette, Alessandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10616275/
https://www.ncbi.nlm.nih.gov/pubmed/37726420
http://dx.doi.org/10.1038/s41423-023-01083-0