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IDO1 facilitates esophageal carcinoma progression by driving the direct binding of NF-κB and CXCL10

Esophageal carcinoma (EC), one of the most lethal human malignancies, lacks effective targeted therapies. Indoleamine 2,3-dioxygenase 1 (IDO1) plays a key role in a variety of cancers, but its role and mechanism in EC are still unclear. Immunohistochemistry and qRT-PCR were used to analyze the expre...

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Detalles Bibliográficos
Autores principales: Yao, Wenjian, Cui, Xiaohai, Peng, Haodong, Zhang, Yongkang, Jia, Xiangbo, Wu, Sen, Zhao, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10616276/
https://www.ncbi.nlm.nih.gov/pubmed/37903782
http://dx.doi.org/10.1038/s41420-023-01689-3