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Vγ9+Vδ2+ T cell control of Listeria monocytogenes growth in infected epithelial cells requires butyrophilin 3A genes

Intracellular bacteria produce antigens, which serve as potent activators of γδ T cells. Phosphoantigens are presented via a complex of butyrophilins (BTN) to signal infection to human Vγ9+Vδ2+ T cells. Here, we established an in vitro system allowing for studies of Vγ9+Vδ2+ T cell activity in cocul...

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Detalles Bibliográficos
Autores principales: Fischer, Katrin, Bradlerova, Michaela, Decker, Thomas, Supper, Verena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10616279/
https://www.ncbi.nlm.nih.gov/pubmed/37903831
http://dx.doi.org/10.1038/s41598-023-45587-1