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OGT/HIF-2α axis promotes the progression of clear cell renal cell carcinoma and regulates its sensitivity to ferroptosis

O-GlcNAc transferase (OGT) acts in the development of various cancers, but its role in clear cell renal cell carcinoma (ccRCC) remains unclear. In this study, we found that OGT was upregulated in ccRCC and this upregulation was associated with a worse survival. Moreover, OGT promoted the proliferati...

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Detalles Bibliográficos
Autores principales: Yang, Zhou, Wei, Xiyi, Ji, Chengjian, Ren, Xiaohan, Su, Wei, Wang, Yichun, Zhou, Jingwan, Zhao, Zheng, Zhou, Pengcheng, Zhao, Kejie, Yao, Bing, Song, Ninghong, Qin, Chao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10616330/
https://www.ncbi.nlm.nih.gov/pubmed/37915611
http://dx.doi.org/10.1016/j.isci.2023.108148