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SUMOylation indirectly suppresses activity of the HIF-1α pathway in intestinal epithelial cells
The hypoxia-inducible factor (HIF) is a master regulator of the cellular transcriptional response to hypoxia. While the oxygen-sensitive regulation of HIF-1α subunit stability via the ubiquitin–proteasome pathway has been well described, less is known about how other oxygen-independent post-translat...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10616383/ https://www.ncbi.nlm.nih.gov/pubmed/37742924 http://dx.doi.org/10.1016/j.jbc.2023.105280 |