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SUMOylation indirectly suppresses activity of the HIF-1α pathway in intestinal epithelial cells

The hypoxia-inducible factor (HIF) is a master regulator of the cellular transcriptional response to hypoxia. While the oxygen-sensitive regulation of HIF-1α subunit stability via the ubiquitin–proteasome pathway has been well described, less is known about how other oxygen-independent post-translat...

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Detalles Bibliográficos
Autores principales:	Malkov, Mykyta I., Flood, Darragh, Taylor, Cormac T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10616383/ https://www.ncbi.nlm.nih.gov/pubmed/37742924 http://dx.doi.org/10.1016/j.jbc.2023.105280

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