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Oral vancomycin treatment suppresses gut trypsin activity and preserves intestinal barrier function during EAE

Studies have reported increased intestinal permeability in multiple sclerosis (MS) patients and its mouse model experimental autoimmune encephalomyelitis (EAE). However, the mechanisms driving increased intestinal permeability that in turn exacerbate neuroinflammation during EAE remain unclear. Here...

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Detalles Bibliográficos
Autores principales: Bianchimano, Paola, Iwanowski, Kacper, Smith, Emma M., Cantor, Adam, Leone, Paola, Bongers, Gerold, Gonzalez, Carlos G., Hongsup, Yoon, Elias, Joshua, Weiner, Howard L., Clemente, Jose C., Tankou, Stephanie K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10616394/
https://www.ncbi.nlm.nih.gov/pubmed/37915599
http://dx.doi.org/10.1016/j.isci.2023.108143