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Proline provides a nitrogen source in the retinal pigment epithelium to synthesize and export amino acids for the neural retina
It is known that metabolic defects in the retinal pigment epithelium (RPE) can cause degeneration of its neighboring photoreceptors in the retina, leading to retinal degenerative diseases such as age-related macular degeneration. However, how RPE metabolism supports the health of the neural retina r...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10616405/ https://www.ncbi.nlm.nih.gov/pubmed/37741457 http://dx.doi.org/10.1016/j.jbc.2023.105275 |