Proline provides a nitrogen source in the retinal pigment epithelium to synthesize and export amino acids for the neural retina

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It is known that metabolic defects in the retinal pigment epithelium (RPE) can cause degeneration of its neighboring photoreceptors in the retina, leading to retinal degenerative diseases such as age-related macular degeneration. However, how RPE metabolism supports the health of the neural retina r...

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Detalles Bibliográficos
Autores principales: Zhu, Siyan, Xu, Rong, Engel, Abbi L., Wang, Yekai, McNeel, Rachel, Hurley, James B., Chao, Jennifer R., Du, Jianhai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10616405/
https://www.ncbi.nlm.nih.gov/pubmed/37741457
http://dx.doi.org/10.1016/j.jbc.2023.105275
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