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Arachidonic acid activates NLRP3 inflammasome in MDSCs via FATP2 to promote post-transplant tumour recurrence in steatotic liver grafts

BACKGROUND & AIMS: The steatotic grafts have been applied in liver transplantation frequently owing to the high incidence of non-alcoholic fatty liver disease. However, fatty livers are vulnerable to graft injury. Myeloid-derived suppressor cell (MDSC) recruitment during liver graft injury promo...

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Detalles Bibliográficos
Autores principales: Liu, Hui, Yeung, Wai Ho Oscar, Pang, Li, Liu, Jiang, Liu, Xiao Bing, Pan Ng, Kevin Tak, Zhang, Qingmei, Qiu, Wen Qi, Zhu, Yueqin, Ding, Tao, Wang, Zhe, Zhu, Ji Ye, Lo, Chung Mau, Man, Kwan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10616418/
https://www.ncbi.nlm.nih.gov/pubmed/37916155
http://dx.doi.org/10.1016/j.jhepr.2023.100895