Cargando…

Deciphering the mechanism of action of VP343, an antileishmanial drug candidate, in Leishmania infantum

Antileishmanial chemotherapy is currently limited due to severe toxic side effects and drug resistance. Hence, new antileishmanial compounds based on alternative approaches, mainly to avoid the emergence of drug resistance, are needed. The present work aims to decipher the mechanism of action of an...

Descripción completa

Detalles Bibliográficos
Autores principales: Obeid, Sameh, Berbel-Manaia, Eloisa, Nicolas, Valérie, Dennemont, Indira, Barbier, Julien, Cintrat, Jean-Christophe, Gillet, Daniel, Loiseau, Philippe M., Pomel, Sébastien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10616420/
https://www.ncbi.nlm.nih.gov/pubmed/37915600
http://dx.doi.org/10.1016/j.isci.2023.108144