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Aquaporin-3 Downregulation in Vitiligo Keratinocytes Increases Oxidative Stress of Melanocytes

Oxidative stress-induced melanocyte apoptosis is linked to the immune system and plays a critical role in the pathogenesis of vitiligo. Aquaporin-3 (AQP3), which is downregulated in vitiligo keratinocytes, regulates intracellular H(2)O(2) accumulation. However, the role of AQP3 in oxidative stress i...

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Detalles Bibliográficos
Autores principales: Kim, Nan-Hyung, Kim, Ha Jung, Lee, Ai-Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Applied Pharmacology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10616513/
https://www.ncbi.nlm.nih.gov/pubmed/37818624
http://dx.doi.org/10.4062/biomolther.2023.112