Synergistic Renoprotective Effect of Melatonin and Zileuton by Inhibition of Ferroptosis via the AKT/mTOR/NRF2 Signaling in Kidney Injury and Fibrosis

According to recent evidence, ferroptosis is a major cell death mechanism in the pathogenesis of kidney injury and fibrosis. Despite the renoprotective effects of classical ferroptosis inhibitors, therapeutic approaches targeting kidney ferroptosis remain limited. In this study, we assessed the reno...

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Detalles Bibliográficos
Autores principales: Jung, Kyung Hee, Kim, Sang Eun, Go, Han Gyeol, Lee, Yun Ji, Park, Min Seok, Ko, Soyeon, Han, Beom Seok, Yoon, Young-Chan, Cho, Ye Jin, Lee, Pureunchowon, Lee, Sang-Ho, Kim, Kipyo, Hong, Soon-Sun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Applied Pharmacology 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10616517/
https://www.ncbi.nlm.nih.gov/pubmed/37183002
http://dx.doi.org/10.4062/biomolther.2023.062

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10616517/
https://www.ncbi.nlm.nih.gov/pubmed/37183002
http://dx.doi.org/10.4062/biomolther.2023.062

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