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Licochalcone H Targets EGFR and AKT to Suppress the Growth of Oxaliplatin -Sensitive and -Resistant Colorectal Cancer Cells

Treatment of colorectal cancer (CRC) has always been challenged by the development of resistance. We investigated the antiproliferative activity of licochalcone H (LCH), a regioisomer of licochalcone C derived from the root of Glycyrrhiza inflata, in oxaliplatin (Ox)-sensitive and -resistant CRC cel...

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Detalles Bibliográficos
Autores principales: Lee, Seung-On, Lee, Mee-Hyun, Kwak, Ah-Won, Lee, Jin-Young, Yoon, Goo, Joo, Sang Hoon, Choi, Yung Hyun, Park, Jin Woo, Shim, Jung-Hyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Applied Pharmacology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10616518/
https://www.ncbi.nlm.nih.gov/pubmed/37899744
http://dx.doi.org/10.4062/biomolther.2023.155