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Methotrexate-conjugated zinc oxide nanoparticles exert a substantially improved cytotoxic effect on lung cancer cells by inducing apoptosis

In the current study, we report the synthesis of methotrexate-conjugated zinc oxide nanoparticles (MTX-ZnONPs) and their high efficacy against lung cancer cells. Conjugation of MTX with ZnONPs was authenticated by UV-vis spectroscopy, dynamic light scattering (DLS), Fourier-transform infrared (FTIR)...

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Detalles Bibliográficos
Autores principales: Mishra, Prakriti, Ali Ahmad, Mohd Faizan, Al-Keridis, Lamya Ahmed, Saeed, Mohd, Alshammari, Nawaf, Alabdallah, Nadiyah M., Tiwari, Rohit Kumar, Ahmad, Afza, Verma, Mahima, Fatima, Shireen, Ansari, Irfan Ahmad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10616591/
https://www.ncbi.nlm.nih.gov/pubmed/37915418
http://dx.doi.org/10.3389/fphar.2023.1194578