Estimating gene-level false discovery probability improves eQTL statistical fine-mapping precision

Statistical fine-mapping prioritizes putative causal variants from a large number of candidate variants, and is widely used in expression quantitative loci (eQTLs) studies. In eQTL fine-mapping, the existence of causal variants for gene expression is not guaranteed, since the genetic heritability of...

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Detalles Bibliográficos
Autores principales: Wang, Qingbo S, Edahiro, Ryuya, Namkoong, Ho, Hasegawa, Takanori, Shirai, Yuya, Sonehara, Kyuto, Kumanogoh, Atsushi, Ishii, Makoto, Koike, Ryuji, Kimura, Akinori, Imoto, Seiya, Miyano, Satoru, Ogawa, Seishi, Kanai, Takanori, Fukunaga, Koichi, Okada, Yukinori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Standard Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10616627/
https://www.ncbi.nlm.nih.gov/pubmed/37915762
http://dx.doi.org/10.1093/nargab/lqad090

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10616627/
https://www.ncbi.nlm.nih.gov/pubmed/37915762
http://dx.doi.org/10.1093/nargab/lqad090

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