Emerging Roles of cGAS-STING Signaling in Mediating Ocular Inflammation

Cyclic GMP-AMP (cGAMP) synthase (cGAS), a sensor of cytosolic DNA, recognizes cytoplasmic nucleic acids to activate the innate immune responses via generation of the second messenger cGAMP and subsequent activation of the stimulator of interferon genes (STINGs). The cGAS-STING signaling has multiple...

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Detalles Bibliográficos
Autores principales: Zhou, Linbin, Ho, Bo Man, Chan, Hoi Ying Emily, Tong, Yan, Du, Lin, He, Jing Na, Ng, Danny Siu-Chun, Tham, Clement C., Pang, Chi Pui, Chu, Wai Kit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2023
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10616671/
https://www.ncbi.nlm.nih.gov/pubmed/37778330
http://dx.doi.org/10.1159/000533897

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10616671/
https://www.ncbi.nlm.nih.gov/pubmed/37778330
http://dx.doi.org/10.1159/000533897

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