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Highly regioselective 6-exo-dig iodo/bromo cyclizations of functionalized 5-amino propargyl pyrimidinones: an efficient synthesis of functionalized pteridines

The manuscript describes the highly regioselective 6-exo-dig iodo/bromo cyclization of functionalized N-propagyl-amino-pyrimidinones under ambient conditions. The cyclization afforded functionalized pteridines in excellent yields. The optimized procedures are mild, operationally simple and working s...

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Detalles Bibliográficos
Autores principales: Naikoo, Rayees Ahmad, Kumar, Rupesh, Sharma, Rashmi, Mahajan, Dinesh, Bhargava, Gaurav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10616752/
https://www.ncbi.nlm.nih.gov/pubmed/37915442
http://dx.doi.org/10.1039/d3ra05651a