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Novel quinoxaline-3-propanamides as VGFR-2 inhibitors and apoptosis inducers

Vascular endothelial growth factor receptor-2 is a vital target for therapeutic mediation in various types of cancer. This study was aimed at exploring the cytotoxic activity of seventeen novel quinoxaline-3-propanamides against colon cancer (HCT-116) and breast cancer (MCF-7) using MTT assay. Resul...

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Detalles Bibliográficos
Autores principales: Ismail, Magda M. F., Shawer, Taghreed Z., Ibrahim, Rabab S., Abusaif, Mostafa S., Kamal, Mona M., Allam, Rasha M., Ammar, Yousry A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10616755/
https://www.ncbi.nlm.nih.gov/pubmed/37915441
http://dx.doi.org/10.1039/d3ra05066a