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N-terminal region is responsible for mHv1 channel activity in MDSCs

Voltage-gated proton channels (Hv1) are important regulators of the immunosuppressive function of myeloid-derived suppressor cells (MDSCs) in mice and have been proposed as a potential therapeutic target to alleviate dysregulated immunosuppression in tumors. However, till date, there is a lack of ev...

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Detalles Bibliográficos
Autores principales: Peña-Pichicoi, Antonio, Fernández, Miguel, Navarro-Quezada, Nieves, Alvear-Arias, Juan J., Carrillo, Christian A., Carmona, Emerson M., Garate, Jose, Lopez-Rodriguez, Angelica M., Neely, Alan, Hernández-Ochoa, Erick O., González, Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10616795/
https://www.ncbi.nlm.nih.gov/pubmed/37915407
http://dx.doi.org/10.3389/fphar.2023.1265130