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N-terminal region is responsible for mHv1 channel activity in MDSCs
Voltage-gated proton channels (Hv1) are important regulators of the immunosuppressive function of myeloid-derived suppressor cells (MDSCs) in mice and have been proposed as a potential therapeutic target to alleviate dysregulated immunosuppression in tumors. However, till date, there is a lack of ev...
Autores principales: | Peña-Pichicoi, Antonio, Fernández, Miguel, Navarro-Quezada, Nieves, Alvear-Arias, Juan J., Carrillo, Christian A., Carmona, Emerson M., Garate, Jose, Lopez-Rodriguez, Angelica M., Neely, Alan, Hernández-Ochoa, Erick O., González, Carlos |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10616795/ https://www.ncbi.nlm.nih.gov/pubmed/37915407 http://dx.doi.org/10.3389/fphar.2023.1265130 |
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