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Heterologous Production and Biosynthesis of Threonine-16:0dioic acids with a Hydroxamate Moiety

[Image: see text] Dereplication and genome mining in Streptomyces aureus LU18118 combined with heterologous expression of selected biosynthetic gene clusters (BGCs) led to the discovery of various threonine-16:0dioic acids named lipothrenins. Lipothrenins consist of the core elements l-Thr, d-allo-T...

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Detalles Bibliográficos
Autores principales: Stierhof, Marc, Myronovskyi, Maksym, Zapp, Josef, Luzhetskyy, Andriy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society and American Society of Pharmacognosy 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10616846/
https://www.ncbi.nlm.nih.gov/pubmed/37728876
http://dx.doi.org/10.1021/acs.jnatprod.3c00097