Comparative analysis of the impact of 40 adenovirus types on dendritic cell activation and CD8(+) T cell proliferation capacity for the identification of favorable immunization vector candidates

For the development of new adenovirus (AdV)-based vectors, it is important to understand differences in immunogenicity. In a side-by-side in vitro analysis, we evaluated the effect of 40 AdV types covering human AdV (HAdV) species A through G on the expression of 11 activation markers and the secret...

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Detalles Bibliográficos
Autores principales: Wang, Xiaoyan, Hetzel, Mario, Zhang, Wenli, Ehrhardt, Anja, Bayer, Wibke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10616870/
https://www.ncbi.nlm.nih.gov/pubmed/37915567
http://dx.doi.org/10.3389/fimmu.2023.1286622

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10616870/
https://www.ncbi.nlm.nih.gov/pubmed/37915567
http://dx.doi.org/10.3389/fimmu.2023.1286622

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