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The MHC Associated Peptide Proteomics assay is a useful tool for the non-clinical assessment of immunogenicity

The propensity of therapeutic proteins to elicit an immune response, poses a significant challenge in clinical development and safety of the patients. Assessment of immunogenicity is crucial to predict potential adverse events and design safer biologics. In this study, we employed MHC Associated Pep...

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Detalles Bibliográficos
Autores principales: Jankowski, Wojciech, Kidchob, Christopher, Bunce, Campbell, Cloake, Edward, Resende, Ricardo, Sauna, Zuben E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10616951/
https://www.ncbi.nlm.nih.gov/pubmed/37915568
http://dx.doi.org/10.3389/fimmu.2023.1271120