Rescue of Alzheimer’s disease phenotype in a mouse model by transplantation of wild-type hematopoietic stem and progenitor cells

Alzheimer’s disease (AD) is the most prevalent cause of dementia; microglia have been implicated in AD pathogenesis, but their role is still matter of debate. Our study showed that single systemic wild-type (WT) hematopoietic stem and progenitor cell (HSPC) transplantation rescued the AD phenotype i...

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Detalles Bibliográficos
Autores principales: Mishra, Priyanka, Silva, Alexander, Sharma, Jay, Nguyen, Jacqueline, Pizzo, Donald P., Hinz, Denise, Sahoo, Debashis, Cherqui, Stephanie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10617121/
https://www.ncbi.nlm.nih.gov/pubmed/37561625
http://dx.doi.org/10.1016/j.celrep.2023.112956

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10617121/
https://www.ncbi.nlm.nih.gov/pubmed/37561625
http://dx.doi.org/10.1016/j.celrep.2023.112956

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