Hypoxia enhances anti-fibrotic properties of extracellular vesicles derived from hiPSCs via the miR302b-3p/TGFβ/SMAD2 axis

BACKGROUND: Cardiac fibrosis is one of the top killers among fibrotic diseases and continues to be a global unaddressed health problem. The lack of effective treatment combined with the considerable socioeconomic burden highlights the urgent need for innovative therapeutic options. Here, we evaluate...

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Detalles Bibliográficos
Autores principales: Paw, Milena, Kusiak, Agnieszka A., Nit, Kinga, Litewka, Jacek J., Piejko, Marcin, Wnuk, Dawid, Sarna, Michał, Fic, Kinga, Stopa, Kinga B., Hammad, Ruba, Barczyk-Woznicka, Olga, Cathomen, Toni, Zuba-Surma, Ewa, Madeja, Zbigniew, Ferdek, Paweł E., Bobis-Wozowicz, Sylwia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10617123/
https://www.ncbi.nlm.nih.gov/pubmed/37904135
http://dx.doi.org/10.1186/s12916-023-03117-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10617123/
https://www.ncbi.nlm.nih.gov/pubmed/37904135
http://dx.doi.org/10.1186/s12916-023-03117-w

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