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Hypoxia enhances anti-fibrotic properties of extracellular vesicles derived from hiPSCs via the miR302b-3p/TGFβ/SMAD2 axis
BACKGROUND: Cardiac fibrosis is one of the top killers among fibrotic diseases and continues to be a global unaddressed health problem. The lack of effective treatment combined with the considerable socioeconomic burden highlights the urgent need for innovative therapeutic options. Here, we evaluate...
Autores principales: | Paw, Milena, Kusiak, Agnieszka A., Nit, Kinga, Litewka, Jacek J., Piejko, Marcin, Wnuk, Dawid, Sarna, Michał, Fic, Kinga, Stopa, Kinga B., Hammad, Ruba, Barczyk-Woznicka, Olga, Cathomen, Toni, Zuba-Surma, Ewa, Madeja, Zbigniew, Ferdek, Paweł E., Bobis-Wozowicz, Sylwia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10617123/ https://www.ncbi.nlm.nih.gov/pubmed/37904135 http://dx.doi.org/10.1186/s12916-023-03117-w |
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