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Primary explants of the postnatal thymus allow the expansion of clonogenic thymic epithelial cells that constitute thymospheres
BACKGROUND: Thymic epithelial cells (TECs) are responsible for shaping the repertoires of T cells, where their postnatal regeneration depends on a subset of clonogenic TECs. Despite the implications for regenerative medicine, their cultivation and expansion remain challenging. Primary explant cell c...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10617125/ https://www.ncbi.nlm.nih.gov/pubmed/37904232 http://dx.doi.org/10.1186/s13287-023-03529-8 |