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Primary explants of the postnatal thymus allow the expansion of clonogenic thymic epithelial cells that constitute thymospheres

BACKGROUND: Thymic epithelial cells (TECs) are responsible for shaping the repertoires of T cells, where their postnatal regeneration depends on a subset of clonogenic TECs. Despite the implications for regenerative medicine, their cultivation and expansion remain challenging. Primary explant cell c...

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Detalles Bibliográficos
Autores principales: Ocampo-Godinez, Juan M., Gonzalez-Quiroz, Jose L., Cote-Palafox, Hector, George, Elizabeth, Vergara-Lope Nuñez, Jael A., Villagomez-Olea, Guillermo, Vazquez-Vazquez, Febe C., Lopez-Villegas, Edgar O., Leon-Avila, Gloria, Dominguez-Lopez, Maria L., Alvarez-Perez, Marco A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10617125/
https://www.ncbi.nlm.nih.gov/pubmed/37904232
http://dx.doi.org/10.1186/s13287-023-03529-8