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Assessing the safety of lipid-modifying medications among Chinese adolescents: a drug-target Mendelian randomization study

BACKGROUND: With increasing hypercholesterolemia prevalence in East Asian adolescents, pharmacologic interventions (e.g., HMGCR inhibitors (statins) and PCSK9 inhibitors) may have to be considered although their longer-term safety in the general adolescent population is unclear. This study aims to i...

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Detalles Bibliográficos
Autores principales: Luo, Shan, Lam, Hugh Simon, Chan, Yap Hang, Tang, Clara Sze Man, He, Baoting, Kwok, Man Ki, Leung, Gabriel M., Schooling, C Mary, Au Yeung, Shiu Lun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10617134/
https://www.ncbi.nlm.nih.gov/pubmed/37904165
http://dx.doi.org/10.1186/s12916-023-03115-y