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Decreased HAT1 expression in granulosa cells disturbs oocyte meiosis during mouse ovarian aging

BACKGROUND: With advanced maternal age, abnormalities during oocyte meiosis increase significantly. Aneuploidy is an important reason for the reduction in the quality of aged oocytes. However, the molecular mechanism of aneuploidy in aged oocytes is far from understood. Histone acetyltransferase 1 (...

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Detalles Bibliográficos
Autores principales: Guo, Bichun, Zhang, Sainan, Wang, Shanshan, Zhang, Huidan, Fang, Junshun, Kang, Nannan, Zhen, Xin, Zhang, Yang, Zhou, Jidong, Yan, Guijun, Sun, Haixiang, Ding, Lijun, Liu, Chuanming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10617186/
https://www.ncbi.nlm.nih.gov/pubmed/37907924
http://dx.doi.org/10.1186/s12958-023-01147-w