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Decreased HAT1 expression in granulosa cells disturbs oocyte meiosis during mouse ovarian aging
BACKGROUND: With advanced maternal age, abnormalities during oocyte meiosis increase significantly. Aneuploidy is an important reason for the reduction in the quality of aged oocytes. However, the molecular mechanism of aneuploidy in aged oocytes is far from understood. Histone acetyltransferase 1 (...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10617186/ https://www.ncbi.nlm.nih.gov/pubmed/37907924 http://dx.doi.org/10.1186/s12958-023-01147-w |