DeepGAMI: deep biologically guided auxiliary learning for multimodal integration and imputation to improve genotype–phenotype prediction

BACKGROUND: Genotypes are strongly associated with disease phenotypes, particularly in brain disorders. However, the molecular and cellular mechanisms behind this association remain elusive. With emerging multimodal data for these mechanisms, machine learning methods can be applied for phenotype pre...

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Detalles Bibliográficos
Autores principales: Chandrashekar, Pramod Bharadwaj, Alatkar, Sayali, Wang, Jiebiao, Hoffman, Gabriel E., He, Chenfeng, Jin, Ting, Khullar, Saniya, Bendl, Jaroslav, Fullard, John F., Roussos, Panos, Wang, Daifeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10617196/
https://www.ncbi.nlm.nih.gov/pubmed/37904203
http://dx.doi.org/10.1186/s13073-023-01248-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10617196/
https://www.ncbi.nlm.nih.gov/pubmed/37904203
http://dx.doi.org/10.1186/s13073-023-01248-6

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