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MLKL regulates Cx43 ubiquitinational degradation and mediates neuronal necroptosis in ipsilateral thalamus after focal cortical infarction

Necroptosis is known to play an important role in the pathophysiology of cerebral ischemia; however, its role in the occurrence of secondary thalamic injury after focal cerebral infarction and the mechanism about how mixed lineage kinase domain-like (MLKL) executes necroptosis in this pathophysiolog...

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Detalles Bibliográficos
Autores principales: Tang, Yanyan, Chu, Quanhong, Xie, Guanfeng, Tan, Yafu, Ye, Ziming, Qin, Chao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10617209/
https://www.ncbi.nlm.nih.gov/pubmed/37904209
http://dx.doi.org/10.1186/s13041-023-01064-4