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Exploring comorbidity and pharmacological treatment patterns in psoriasis - a retrospective population-based cross-sectional study

BACKGROUND: Individuals with psoriasis face an increased risk of suffering from various comorbid conditions. However, there haven´t been any studies conducted in Sweden to examine the frequency of comorbidities and the corresponding treatment for these conditions among psoriasis patients. METHODS: T...

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Autores principales: Hamgård, Nelly, Duvetorp, Albert, Hägg, Anna, Jerkovic Gullin, Sandra, Seifert, Oliver
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10617277/
https://www.ncbi.nlm.nih.gov/pubmed/37915465
http://dx.doi.org/10.1177/26335565231212336
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author Hamgård, Nelly
Duvetorp, Albert
Hägg, Anna
Jerkovic Gullin, Sandra
Seifert, Oliver
author_facet Hamgård, Nelly
Duvetorp, Albert
Hägg, Anna
Jerkovic Gullin, Sandra
Seifert, Oliver
author_sort Hamgård, Nelly
collection PubMed
description BACKGROUND: Individuals with psoriasis face an increased risk of suffering from various comorbid conditions. However, there haven´t been any studies conducted in Sweden to examine the frequency of comorbidities and the corresponding treatment for these conditions among psoriasis patients. METHODS: The Cosmic electronic medical record represents a comprehensive repository of medical information including all residents of Region Jönköping. To conduct a population-based retrospective cross-sectional study, all individuals diagnosed with psoriasis between April 9, 2008 and July 1, 2016, were identified via the electronic medical records using ICD-10 codes. Data on comorbidity and dispensation of prescribed drugs against these comorbid conditions were analyzed. RESULTS: During the study period, 1.7% of the population (4,587 individuals) were diagnosed with psoriasis, with 74.3% of cases classified as mild to moderate psoriasis and 25.7% as severe. The remaining 268,949 individuals did not receive a psoriasis diagnosis. The study showed that psoriasis patients had higher odds of experiencing the majority of the comorbid conditions examined. Arthritis other than psoriasis arthritis was found to be the most prevalent comorbid diagnosis among psoriasis patients (adjusted OR 7.2, CI 95% 6.4-8.2, p < 0.001), followed by obesity (OR 2.4, CI 95% 1.9-3.1, p < 0,001). There was no significant difference in drug prescription for comorbid diseases between patients with psoriasis and patients without psoriasis except for arthritis and smoking cessation treatment. CONCLUSIONS: Individuals with psoriasis are more susceptible to experiencing multiple comorbid conditions compared to the general population, particularly those with severe psoriasis. There is no evidence of undertreatment of comorbidity except for arthritis among psoriasis patients.
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spelling pubmed-106172772023-11-01 Exploring comorbidity and pharmacological treatment patterns in psoriasis - a retrospective population-based cross-sectional study Hamgård, Nelly Duvetorp, Albert Hägg, Anna Jerkovic Gullin, Sandra Seifert, Oliver J Multimorb Comorb Original Article BACKGROUND: Individuals with psoriasis face an increased risk of suffering from various comorbid conditions. However, there haven´t been any studies conducted in Sweden to examine the frequency of comorbidities and the corresponding treatment for these conditions among psoriasis patients. METHODS: The Cosmic electronic medical record represents a comprehensive repository of medical information including all residents of Region Jönköping. To conduct a population-based retrospective cross-sectional study, all individuals diagnosed with psoriasis between April 9, 2008 and July 1, 2016, were identified via the electronic medical records using ICD-10 codes. Data on comorbidity and dispensation of prescribed drugs against these comorbid conditions were analyzed. RESULTS: During the study period, 1.7% of the population (4,587 individuals) were diagnosed with psoriasis, with 74.3% of cases classified as mild to moderate psoriasis and 25.7% as severe. The remaining 268,949 individuals did not receive a psoriasis diagnosis. The study showed that psoriasis patients had higher odds of experiencing the majority of the comorbid conditions examined. Arthritis other than psoriasis arthritis was found to be the most prevalent comorbid diagnosis among psoriasis patients (adjusted OR 7.2, CI 95% 6.4-8.2, p < 0.001), followed by obesity (OR 2.4, CI 95% 1.9-3.1, p < 0,001). There was no significant difference in drug prescription for comorbid diseases between patients with psoriasis and patients without psoriasis except for arthritis and smoking cessation treatment. CONCLUSIONS: Individuals with psoriasis are more susceptible to experiencing multiple comorbid conditions compared to the general population, particularly those with severe psoriasis. There is no evidence of undertreatment of comorbidity except for arthritis among psoriasis patients. SAGE Publications 2023-10-30 /pmc/articles/PMC10617277/ /pubmed/37915465 http://dx.doi.org/10.1177/26335565231212336 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/This article is distributed under the terms of the Creative Commons Attribution 4.0 License (https://creativecommons.org/licenses/by/4.0/) which permits any use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Original Article
Hamgård, Nelly
Duvetorp, Albert
Hägg, Anna
Jerkovic Gullin, Sandra
Seifert, Oliver
Exploring comorbidity and pharmacological treatment patterns in psoriasis - a retrospective population-based cross-sectional study
title Exploring comorbidity and pharmacological treatment patterns in psoriasis - a retrospective population-based cross-sectional study
title_full Exploring comorbidity and pharmacological treatment patterns in psoriasis - a retrospective population-based cross-sectional study
title_fullStr Exploring comorbidity and pharmacological treatment patterns in psoriasis - a retrospective population-based cross-sectional study
title_full_unstemmed Exploring comorbidity and pharmacological treatment patterns in psoriasis - a retrospective population-based cross-sectional study
title_short Exploring comorbidity and pharmacological treatment patterns in psoriasis - a retrospective population-based cross-sectional study
title_sort exploring comorbidity and pharmacological treatment patterns in psoriasis - a retrospective population-based cross-sectional study
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10617277/
https://www.ncbi.nlm.nih.gov/pubmed/37915465
http://dx.doi.org/10.1177/26335565231212336
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