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Design and rationale for the SIB trial: a randomized parallel comparison of semaglutide versus placebo on intestinal barrier function in type 2 diabetes mellitus

OBJECTIVE: To describe the rationale and design of the SIB trial, an interventional clinical trial testing the hypothesis that subcutaneous (s.c.) once-weekly semaglutide can improve intestinal permeability and reduce systemic inflammation in participants with type 2 diabetes (T2D) and obesity. METH...

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Detalles Bibliográficos
Autores principales: Rella, Steven, Onyiah, Joseph, Baker, Chelsea, Singh, Vatsala, Her, Andrew, Rasouli, Neda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10617296/
https://www.ncbi.nlm.nih.gov/pubmed/37916028
http://dx.doi.org/10.1177/20420188231207348