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Mosaic HIV-1 vaccination induces anti-viral CD8(+) T cell functionality in the phase 1/2a clinical trial APPROACH

The ability of vaccine-induced T cells to inhibit viral replication may contribute to protect against human immunodeficiency virus (HIV) acquisition. Here, we tested ex vivo viral inhibitory activity of T cell responses induced by a multivalent HIV vaccine based on the replication-incompetent recomb...

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Detalles Bibliográficos
Autores principales: van Duijn, Janine, Stieh, Daniel, Fernandez, Natalia, King, Deborah, Gilmour, Jill, Tolboom, Jeroen, Callewaert, Katleen, Willems, Wouter, Pau, Maria G., De Rosa, Stephen C., McElrath, M. Juliana, Barouch, Dan H., Hayes, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10617392/
https://www.ncbi.nlm.nih.gov/pubmed/37811993
http://dx.doi.org/10.1128/jvi.01126-23