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Distinct motifs in the E protein are required for SARS-CoV-2 virus particle formation and lysosomal deacidification in host cells

Severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) is a major public health concern, but the mechanisms underlying its viral particle formation are not well understood. In this study, we established a system for producing virus-like particles (VLPs) by expressing four structural proteins t...

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Detalles Bibliográficos
Autores principales: Miura, Koya, Suzuki, Youichi, Ishida, Kotaro, Arakawa, Masashi, Wu, Hong, Fujioka, Yoshihiko, Emi, Akino, Maeda, Koki, Hamajima, Ryusei, Nakano, Takashi, Tenno, Takeshi, Hiroaki, Hidekazu, Morita, Eiji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10617393/
https://www.ncbi.nlm.nih.gov/pubmed/37830820
http://dx.doi.org/10.1128/jvi.00426-23