Identification of tanshinone I as cap-dependent endonuclease inhibitor with broad-spectrum antiviral effect

The cap-snatching mechanism mediated by cap-dependent endonuclease, which is common among the negative-stranded, segmented RNA viruses in Orthomyxoviridae, Bunyaviridae, and Arenaviridae, is crucial for viral transcription and replication and is thus an attractive target for antiviral drug developme...

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Detalles Bibliográficos
Autores principales: He, Xiaoxue, Yang, Fan, Wu, Yan, Lu, Jia, Gao, Xiao, Zhu, Xuerui, Yang, Jie, Liu, Shuwen, Xiao, Gengfu, Pan, Xiaoyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Vaccines and Antiviral Agents
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10617418/
https://www.ncbi.nlm.nih.gov/pubmed/37732786
http://dx.doi.org/10.1128/jvi.00796-23

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10617418/
https://www.ncbi.nlm.nih.gov/pubmed/37732786
http://dx.doi.org/10.1128/jvi.00796-23

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