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Reovirus genomic diversity confers plasticity for protease utility during adaptation to intracellular uncoating

Mammalian orthoreoviruses (reoviruses) infect many mammals and provide a safe model to study enteric viruses. Knowledge of reoviruses is derived from prototypic lab strains, notably T1L and T3D. Based on these prototypic strains, reoviruses can efficiently utilize gut or lysosomal proteases for unco...

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Detalles Bibliográficos
Autores principales: Lin, Qi Feng, Wong, Casey X. L., Eaton, Heather E., Pang, Xiaoli, Shmulevitz, Maya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10617468/
https://www.ncbi.nlm.nih.gov/pubmed/37747236
http://dx.doi.org/10.1128/jvi.00828-23