Direct interaction with the BRD4 carboxyl-terminal motif (CTM) and TopBP1 is required for human papillomavirus 16 E2 association with mitotic chromatin and plasmid segregation function

During the human papillomavirus 16 (HPV16) life cycle, the E2 protein binds simultaneously to the viral genome and host chromatin throughout mitosis, ensuring viral genomes reside in daughter cell nuclei following cell division. Previously, we demonstrated that CK2 phosphorylation of E2 on serine 23...

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Detalles Bibliográficos
Autores principales: Prabhakar, Apurva T., James, Claire D., Fontan, Christian T., Otoa, Raymonde, Wang, Xu, Bristol, Molly L., Yeager, Calvin, Hill, Ronald D., Dubey, Aanchal, Wu, Shwu-Yuan, Chiang, Cheng-Ming, Morgan, Iain M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Virus-Cell Interactions
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10617519/
https://www.ncbi.nlm.nih.gov/pubmed/37712702
http://dx.doi.org/10.1128/jvi.00782-23

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10617519/
https://www.ncbi.nlm.nih.gov/pubmed/37712702
http://dx.doi.org/10.1128/jvi.00782-23

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