4-Octyl itaconate reduces influenza A replication by targeting the nuclear export protein CRM1

In recent years, especially since the outbreak of the severe acute respiratory syndrome coronavirus 2 pandemic, the cell-permeable itaconate derivative 4-octyl itaconate (4-OI) has gained traction as a potential antiviral agent. Here, we demonstrate that 4-OI inhibits replication of multiple influen...

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Detalles Bibliográficos
Autores principales: Ribó-Molina, Pau, Weiss, Hauke J., Susma, Balasubramanian, van Nieuwkoop, Stefan, Persoons, Leentje, Zheng, Yunan, Ruzek, Melanie, Daelemans, Dirk, Fouchier, Ron A. M., O'Neill, Luke A. J., van den Hoogen, Bernadette G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Vaccines and Antiviral Agents
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10617539/
https://www.ncbi.nlm.nih.gov/pubmed/37823646
http://dx.doi.org/10.1128/jvi.01325-23

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10617539/
https://www.ncbi.nlm.nih.gov/pubmed/37823646
http://dx.doi.org/10.1128/jvi.01325-23

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