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Key role for Rac in the early transcriptional response to extracellular matrix stiffness and stiffness-dependent repression of ATF3
The Rho family GTPases Rac and Rho play critical roles in transmitting mechanical information contained within the extracellular matrix (ECM) to the cell. Rac and Rho have well-described roles in regulating stiffness-dependent actin remodeling, proliferation and motility. However, much less is known...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10617619/ https://www.ncbi.nlm.nih.gov/pubmed/37737020 http://dx.doi.org/10.1242/jcs.260636 |