Caudal Fgfr1 disruption produces localised spinal mis-patterning and a terminal myelocystocele-like phenotype in mice

Closed spinal dysraphisms are poorly understood malformations classified as neural tube (NT) defects. Several, including terminal myelocystocele, affect the distal spine. We have previously identified a NT closure-initiating point, Closure 5, in the distal spine of mice. Here, we document equivalent...

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Detalles Bibliográficos
Autores principales: Maniou, Eirini, Farah, Faduma, Marshall, Abigail R., Crane-Smith, Zoe, Krstevski, Andrea, Stathopoulou, Athanasia, Greene, Nicholas D. E., Copp, Andrew J., Galea, Gabriel L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10617625/
https://www.ncbi.nlm.nih.gov/pubmed/37756583
http://dx.doi.org/10.1242/dev.202139

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10617625/
https://www.ncbi.nlm.nih.gov/pubmed/37756583
http://dx.doi.org/10.1242/dev.202139

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