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SIN-3 acts in distinct complexes to regulate the germline transcriptional program in Caenorhabditis elegans

The transcriptional co-regulator SIN3 influences gene expression through multiple interactions that include histone deacetylases. Haploinsufficiency and mutations in SIN3 are the underlying cause of Witteveen–Kolk syndrome and related intellectual disability and autism syndromes, emphasizing its key...

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Detalles Bibliográficos
Autores principales: Robert, Valerie J., Caron, Matthieu, Gely, Loic, Adrait, Annie, Pakulska, Victoria, Couté, Yohann, Chevalier, Manon, Riedel, Christian G., Bedet, Cecile, Palladino, Francesca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10617626/
https://www.ncbi.nlm.nih.gov/pubmed/37818613
http://dx.doi.org/10.1242/dev.201755