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SIN-3 acts in distinct complexes to regulate the germline transcriptional program in Caenorhabditis elegans
The transcriptional co-regulator SIN3 influences gene expression through multiple interactions that include histone deacetylases. Haploinsufficiency and mutations in SIN3 are the underlying cause of Witteveen–Kolk syndrome and related intellectual disability and autism syndromes, emphasizing its key...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10617626/ https://www.ncbi.nlm.nih.gov/pubmed/37818613 http://dx.doi.org/10.1242/dev.201755 |