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Genomic insights into the mechanisms of FGFR1 dependency in squamous cell lung cancer

Although subsets of patients with lung squamous cell carcinoma (LSCC) benefit from immunotherapy, there are few effective molecularly targeted treatments for LSCC. Fibroblast growth factor receptor (FGFR) inhibitors provide a therapeutic option for patients with LSCC harboring FGFR aberrations, but...

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Detalles Bibliográficos
Autores principales: Mäkinen, Netta, Meyerson, Matthew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10617760/
https://www.ncbi.nlm.nih.gov/pubmed/37909331
http://dx.doi.org/10.1172/JCI174171