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Heterogeneity in allospecific T cell function in transplant-tolerant hosts determines susceptibility to rejection following infection

Even when successfully induced, immunological tolerance to solid organs remains vulnerable to inflammatory insults, which can trigger rejection. In a mouse model of cardiac allograft tolerance in which infection with Listeria monocytogenes (Lm) precipitates rejection of previously accepted grafts, w...

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Detalles Bibliográficos
Autores principales: McIntosh, Christine M., Allocco, Jennifer B., Wang, Peter, McKeague, Michelle L., Cassano, Alexandra, Wang, Ying, Xie, Stephen Z., Hynes, Grace, Mora-Cartín, Ricardo, Abbondanza, Domenic, Chen, Luqiu, Sattar, Husain, Yin, Dengping, Zhang, Zheng J., Chong, Anita S., Alegre, Maria-Luisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10617766/
https://www.ncbi.nlm.nih.gov/pubmed/37676735
http://dx.doi.org/10.1172/JCI168465