Multiscale genetic architecture of donor-recipient differences reveals intronic LIMS1 mismatches associated with kidney transplant survival

Donor-recipient (D-R) mismatches outside of human leukocyte antigens (HLAs) contribute to kidney allograft loss, but the mechanisms remain unclear, specifically for intronic mismatches. We quantified non-HLA mismatches at variant-, gene-, and genome-wide scales from single nucleotide polymorphism (S...

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Detalles Bibliográficos
Autores principales: Sun, Zeguo, Zhang, Zhongyang, Banu, Khadija, Gibson, Ian W., Colvin, Robert B., Yi, Zhengzi, Zhang, Weijia, De Kumar, Bony, Reghuvaran, Anand, Pell, John, Manes, Thomas D., Djamali, Arjang, Gallon, Lorenzo, O’Connell, Philip J., He, John Cijiang, Pober, Jordan S., Heeger, Peter S., Menon, Madhav C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10617779/
https://www.ncbi.nlm.nih.gov/pubmed/37676733
http://dx.doi.org/10.1172/JCI170420

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10617779/
https://www.ncbi.nlm.nih.gov/pubmed/37676733
http://dx.doi.org/10.1172/JCI170420

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