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Acyl-CoA synthase ACSL4: an essential target in ferroptosis and fatty acid metabolism

Long-chain acyl-coenzyme A (CoA) synthase 4 (ACSL4) is an enzyme that esterifies CoA into specific polyunsaturated fatty acids, such as arachidonic acid and adrenic acid. Based on accumulated evidence, the ACSL4-catalyzed biosynthesis of arachidonoyl-CoA contributes to the execution of ferroptosis b...

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Detalles Bibliográficos
Autores principales: Ding, Kaiyue, Liu, Chongbin, Li, Li, Yang, Ming, Jiang, Na, Luo, Shilu, Sun, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10617883/
https://www.ncbi.nlm.nih.gov/pubmed/37442770
http://dx.doi.org/10.1097/CM9.0000000000002533